How to Handle a Stress-Related Psychosomatic Illness

stressed woman with her head in her hands at work desk

Jamie Grill / Getty Images

In Greek, psyche refers to the mind or soul, and somatic refers to the body. In essence, the term psychosomatic captures the mind-body connection. The World Health Organization defines psychosomatic medicine as “the study of biological, psychological, and social variables in health and disease.”

Psychosomatic illness involves experiencing physical symptoms that are the body's response to stress. In contrast, somatopsychic illness would be the psychological symptoms caused by disease, injury, or infection.

Stress-related illness is very common, but people often mistakenly think that the physical symptoms caused by stress are not serious. In fact, chronic stress can cause physical symptoms that have a grave impact on your health, and without intervention, can lead to diseases such as heart disease, diabetes, and digestive issues that can shorten one's lifespan.

In this article, we will explore the biological mechanisms that link the mind and the body in the disease process and dispel the myth that these illnesses are "all in your mind." You will learn more about current views of psychosomatic illness, common stress-related health symptoms, and the appropriate treatment.

An estimated 60 to 80% of primary care visits are due to health problems influenced at least in part by stress, indicating the psychosomatic response to stress is more common than people realize.

Stress

No one is immune from experiencing stress in life. There are daily hassles, like dealing with traffic, working with a demanding boss, and managing a busy schedule. There are also major stressors such as poverty, maltreatment, relationship problems, job loss, caregiving, and traumatic events.

The burden of chronic stress can take its toll on the human body through the "biological embedding" of a maladaptive stress response, especially in childhood if the brain is developing through a variety of adverse experiences. Without intervention, this maladaptive stress response can carry on through adulthood. Neuroplasticity of the brain, or the ability for neurons to adapt and re-wire, gives hope for recovery from the damaging effects of stress.

The way we perceive and cope with stress will also be a determining factor in the development of psychosomatic issues. There can be an additional layer of damage added to our health caused by negative coping behaviors related to diet, exercise, smoking, alcohol use, drugs, etc. On the other hand, social support, positive coping strategies, and a healthy lifestyle are mediators in the pathway between the mind and the body that can minimize the impact of stress on your health.

Types of Stress-Related Symptoms

When you are under stress that exceeds your ability to cope, you are likely to experience physical symptoms. These can include aches, pains, muscle spasms, and headaches, possibly from unconsciously tensing your muscles for extended periods. Your stomach may be upset from the impact of stress hormones. And you may not be sleeping well, leaving you feeling fatigued and burnt out.

Some common examples of symptoms that a person might experience as a result of stress include:

  • Body aches
  • Cognitive problems (foggy brain, forgetful)
  • Decreased sex drive/erectile dysfunction
  • Digestive issues (diarrhea, constipation)
  • Fatigue
  • Grinding teeth
  • Hair loss
  • Headaches and migraines
  • High blood pressure
  • Insomnia or hypersomnia
  • Muscle tension
  • Pain (back pain, stomach pain, etc.)
  • Skin rashes
  • Weight changes

It is important to note that this does not mean that these symptoms are always caused by stress, and there may be medical causes that need to be identified.

If you are experiencing these problems, you should talk to your healthcare provider in order to identify the root cause and receive appropriate treatment.

Psychosomatic Illness

Stress can cause a variety of symptoms, as seen above. These symptoms are mediated through the immune system, the nervous system, and the endocrine system. Over time, if left unchecked, this can lead to disruption in the delicate balance of hormones, neurotransmitters, metabolic processes, and the immune response that is required to maintain health. These systemic changes contribute, at least in part, to the development of illness and disease, that oftentimes could be prevented.

Examples of illness and disease influenced by stress:

  • Arthritis
  • Dementia
  • Diabetes
  • Gum disease
  • Heart disease
  • High blood pressure
  • Hyperthyroid
  • Irritable bowel syndrome
  • Metabolic syndrome
  • Obesity
  • Osteoporosis
  • Stomach ulcer
  • Stroke

The Biological Mechanisms Linking Mind and Body

One of the main culprits in this disease process is the stress hormone known as cortisol. When someone perceives a threat in their environment, the emotional processing center in the brain, the amygdala, sends out an alarm signal. Through neuroendocrine hormones, the signal is picked up by the hypothalamus, which triggers the pituitary gland, and then the adrenal glands where stress hormones like adrenaline and cortisol are produced. This is known as the hypothalamus-pituitary-adrenal (HPA) axis, and is responsible for the "fight or flight" response.

What Is Cortisol?

Cortisol is a steroid hormone secreted by the adrenal glands. It plays an important part in the body's stress response, the sleep-wake cycle, and metabolism. When a person is under stress, cortisol helps prepare the body to deal with the threat. However, too much cortisol is bad for health and can contribute to high blood pressure, impaired cognition, increased inflammation, lower immunity, and other health consequences

Sympathetic Nervous System: During the fight or flight response, cortisol affects a wide range of body functions through the sympathetic nervous system. Heart rate increases, blood pressure rises, breathing becomes more shallow and rapid, pupils dilate, blood sugar is released into the blood, and blood flow rushes to the large muscle groups and the brain. There is also an immune response in preparation to heal damaged tissue, and digestion is put on hold. Your body systems are being appropriately mobilized to manage the threat.

Metabolism: Cortisol directs the metabolism of sugar and fats and is a helpful anti-inflammatory under normal circumstances. However, excess cortisol can lead to metabolic problems like high cholesterol, increased appetite, weight gain, decreased insulin sensitivity, high blood sugar, adrenal insufficiency, fatigue, sleep issues, and so on. In addition, the gut microbiome is altered as a response to stress, resulting in a release of toxins, metabolites, and neurohormones that in turn affect eating behavior, mood, energy, and immune functioning.

Immune System: A review of the research published in 2015, shows that people who experience chronic stress have signs of a dysregulated immune system with higher levels of pro-inflammatory cytokines in their bloodstream, lower antibody response to viruses, more frequent illness, and even re-activation of latent viruses like Epstein-Barr. People with ongoing stress also experience more auto-immune flare-ups and slower wound healing. All of these immune system responses place an extra burden on the immune system.

Biological Aging: It is worth mentioning, that there are signs of advanced biological aging at the cellular level indicated by shorter telomeres (the protective end cap of the chromosome).

The impact of cortisol on multiple body systems is why too much of this stress hormone, particularly over a long period, can literally "get under your skin" and lead to major health issues.

Treatment for Psychosomatic Symptoms

Fortunately, the symptoms that manifest can lead you to see a doctor, who then may rule in or rule out any disease process that might be causing them. Without a diagnosis, you may only get treatment aimed at relieving the symptoms, rather than getting at the root cause.

Your healthcare provider may refer you to a mental health professional to help address some of the psychological and emotional factors contributing to your illness.

Psychological treatments and stress management are important, but this does not mean that psychosomatic illnesses do not require medical treatment. Medications may be prescribed to help treat the medical symptoms that you are experiencing.

Psychotherapy

Research suggests that cognitive behavioral therapy (CBT) can be effective in treating stress-related disorders. CBT can minimize stress by correcting faulty thinking habits and negative core beliefs, reducing avoidance behaviors, and building positive coping skills. You can also learn relaxation techniques that activate the parasympathetic nervous system to counteract some of the effects of cortisol.

Mindfulness-based stress reduction (MBSR) may also help reduce stress levels and improve coping skills.

Medications

Your healthcare provider or therapist may also prescribe medications such as antidepressants or anti-anxiety medications. Mental health conditions such as depression and anxiety can contribute to physical symptoms, so medications such as selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines may be helpful for improving well-being.

Self-Help

Self-help may also be an effective tool for reducing medically unexplained symptoms and improving quality of life. Research suggests that self-guided stress management (such as journaling and meditation techniques) can help manage symptoms of stress. However, this approach may be best utilized as a first step or as part of a more comprehensive treatment program.

Relieving Stress for Health

If you are experiencing health concerns that might be related to stress, your first step should be to talk to your healthcare provider. However, there are also steps you can take to relieve stress and improve your overall health. To stay healthy, learn positive ways to deal with stress and eliminate excessive stress from your life whenever possible.

It may seem overwhelming to even think about, but slow and steady, figure out what works for you and what doesn't, and build a new lifestyle that supports your mental and physical health. Strategies that may be helpful for reducing stress levels include:

There are dozens of stress-relieving tactics available, so it is important to learn what stress relievers work best for you. Create a stress management game plan to examine and change the stress in your life. By maintaining healthy habits, you can minimize the stress in your life and reduce the impact of stress-related psychosomatic illness on your health and well-being.

Frequently Asked Questions

  • How can you tell if something is psychosomatic?

    If you experience physical symptoms in the absence of an injury, disease, or illness, there is a chance your symptoms might be psychosomatic or stress-related. It is important to talk to your healthcare provider for an assessment and diagnosis. If no medical causes are found, your healthcare provider can recommend treatments to address symptoms, work with you to manage stress, and refer you to a mental health professional for further assistance.

  • Do psychosomatic symptoms feel real?

    Psychosomatic symptoms are real. While they may be attributed to stress or psychological origins, they have a very real impact on your body. Psychosomatic symptoms are not "all in your head" or imaginary. They are real symptoms that require real treatments. Unfortunately, stigma about psychosomatic illness often leads people to avoid seeking treatment.

  • What medications can help psychosomatic illness?

    Medications such as antidepressants or anti-anxiety drugs may be prescribed to help treat some of the psychological issues that are contributing to symptoms. Other medications may also be prescribed to help alleviate symptoms of muscle pain, stomach upset, and headache. Medical treatments may also be needed to treat conditions that are caused by chronic stress, such as problems with blood glucose levels and elevated blood pressure.

10 Sources
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Bransfield RC, Friedman KJ. Differentiating psychosomatic, somatopsychic, multisystem illnesses, and medical uncertaintyHealthcare (Basel). 2019;7(4):114. doi:10.3390/healthcare7040114

  2. Nerurkar A, Bitton A, Davis RB, Phillips RS, Yeh G. When physicians counsel about stress: Results of a national studyJAMA Intern Med. 2013;173(1):76-77. doi:10.1001/2013.jamainternmed.480

  3. McEwen BS. Brain on stress: How the social environment gets under the skinProc Natl Acad Sci USA. 2012;109(supplement_2):17180-17185. doi:10.1073%2Fpnas.1121254109

  4. American Psychological Association. How stress affects your health.

  5. Madison A, Kiecolt-Glaser JK. Stress, depression, diet, and the gut microbiota: human–bacteria interactions at the core of psychoneuroimmunology and nutritionCurrent Opinion in Behavioral Sciences. 2019;28:105-110. doi:10.1016%2Fj.cobeha.2019.01.011

  6. Morey JN, Boggero IA, Scott AB, Segerstrom SC. Current directions in stress and human immune functionCurrent Opinion in Psychology. 2015;5:13-17. doi:10.1016%2Fj.copsyc.2015.03.007

  7. Nakao M, Shirotsuki K, Sugaya N. Cognitive-behavioral therapy for management of mental health and stress-related disorders: Recent advances in techniques and technologiesBiopsychosoc Med. 2021;15(1):16. doi:10.1186/s13030-021-00219-w

  8. Amanvermez Y, Zhao R, Cuijpers P, et al. Effects of self-guided stress management interventions in college students: A systematic review and meta-analysis. Internet Interv. 2022;28:100503. doi:10.1016/j.invent.2022.100503

  9. Mental Health America of Eastern Missouri. Psychosomatic symptoms.

  10. von dem Knesebeck O, Lehmann M, Löwe B, Makowski AC. Public stigma towards individuals with somatic symptom disorders - Survey results from GermanyJ Psychosom Res. 2018;115:71-75. doi:10.1016/j.jpsychores.2018.10.014

Additional Reading

By Elizabeth Scott, PhD
Elizabeth Scott, PhD is an author, workshop leader, educator, and award-winning blogger on stress management, positive psychology, relationships, and emotional wellbeing.